Wednesday, March 31, 2021
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Covid-19 research advances HIV vaccine work and vice versa


Between AIDS and Covid-19 is a game of communicating vessels. While the health crisis has a negative impact on the screening and monitoring of patients with HIV, it also has a positive effect on research. Indeed, messenger RNA vaccines against Covid-19 have inspired scientists who have been looking for a vaccine against the AIDS virus for 40 years. “It is an innovation in infectious disease which has shown its effectiveness for covid so this bridge to HIV is quite natural and even encouraged”, explains Serawit Bruck-Landais, director of the Sidaction research unit, whose 2021 edition starts on Friday March 26.

More complex than Covid-19, HIV mutates more quickly, so the immune system has more difficulty fighting it. Despite everything, messenger RNA is an interesting avenue for researchers. “A team in Lyon is working on it”, precise Serawit Bruck-Landais. The researcher also evokes dinternational business collaborations to “to see if this vaccine strategy is applicable for HIV. For now it is the very beginning”.

In France, 170,000 people are infected with HIV, nearly 25,000 of whom are unaware that they are carriers of the virus and continue to spread the disease. As a result, there are 6,200 new cases each year.

On the other hand, research on HIV is also advancing that on Covid-19. In France, the Vaccine Research Institute is developing a preventive vaccine against HIV, phase one of which, that of clinical trials on humans, begins in April. This preventive vaccine will send antibodies loaded with fragments of the virus directly onto cells, such as missiles, in order to trigger an immune response. This same process is at the heart of a vaccine project against the variants of Covid-19.

On the one hand, we have this missile which will directly bring to the dendritic cell (cell responsible for triggering the immune response) and on the other side, we can define the fragments of the viruses against which we want to protect ourselves, indicates the pProfessor Yves Levy, Director of the Vaccine Research Institute. NWe were able to put Covid-19 vaccines into production that include the new variants. ” Thanks to his research on HIV, Professor Yves Levy therefore hopes to offer a second generation vaccine against Covid variants from 2022.

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Source site www.francetvinfo.fr

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