Thursday, January 21, 2021
Home Health & Fitness Moderna's Phase 3 Vaccine Results Show Effectiveness

Moderna’s Phase 3 Vaccine Results Show Effectiveness


#In a peer-reviewed publication, #Moderna’s vaccine against #Covid-19 disease is 94% effective.

The #Phase 3 clinical trial of #Moderna’s vaccine against the SARS-CoV-2 coronavirus is based on 30,420 volunteers. They are divided into two groups (of 15,210 participants each): a placebo group; a vaccinated group. The results of this study have just been published on #December 30, 2020, after having been examined by an independent committee (peer-reviewed), in the #New #England #Journal of #Medicine (NEJM).

The publication shows that #Moderna’s vaccine, based on messenger RNA, achieves a final efficacy of 94.1%. #This result is very close to that of #Pfizer (95%), also based on mRNA and which is already generalized in several countries around the world, including #France.

#In purple, the incidence curve in the placebo group. #In orange, the incidence curve in the vaccinated group. #After the 2nd dose, the difference is notable on the graph: the incidence rate is very low in the vaccinated group. // #Source: NEJM / #Moderna / #Numerama
- Advertisement -

#More than 14 days after the second dose – performed 28 days after the first and needed for the vaccine to take full effect – researchers recorded 196 cases of coronavirus infection among the 40,000 participants. #Of these 196 cases, 185 occurred in the placebo group (non-vaccinated), and 11 in the vaccinated group. The incidence rate is much lower in the vaccinated group, which proves a high efficacy of #Moderna’s vaccine against the occurrence of #Covid-19 disease in symptomatic form.

#Regarding asymptomatic transmission, like #Pfizer’s vaccine, #Moderna’s results do not yet allow a strict conclusion to be reached. #However, ” preliminary trial data suggest that there may be some degree of prevention of asymptomatic infection after a single dose ”#Notes the #National #Institute of #Health. #Specific analyzes are underway on this effect of vaccines.

#No noticeable side effects

#Among the cases of infection that occurred in the vaccinated group, no participant did not face severe forms of the #Covid-19 disease. #Moderna’s vaccine therefore appears to protect against severe symptoms, even if infection develops in these few cases.

#Moderna’s publication in theENJM furthermore shows that there are no significant side effects, apart from those usual and foreseen by the authors. #About 50% of the vaccinated volunteers experienced moderate or severe side effects (fatigue, muscle pain, migraine, pain at the injection site) after the second dose, but these effects, classic for a vaccine, were generally resolved. within two days after the injection.

#In the #United #States, the vaccination campaign began in mid-December and #Moderna’s vaccine was quickly validated – #Kamala #Harris, future vice-president, recently received it to reassure the population. The #European #Union plans to postpone its decision on this vaccine on #January 6, 2021. #In anticipation, 80 million doses have been secured, thus making it possible to vaccinate 40 million people.

#Photo credit of the one:
#Pexels / #Moderna #Logo / #Numerama #Editing

#Share on social media

The continuation in video



[ source link ]
https://www.numerama.com/sciences/679262-les-resultats-de-la-phase-3-du-vaccin-de-moderna-montrent-son-efficacite.html

##Modernas ##Phase ##Vaccine ##Results ##Show ##Effectiveness

LEAVE A REPLY

Please enter your comment!
Please enter your name here

Most Popular

Recent Comments